Looking back to a study published by Balogh, L. 2008; Absorption of Oral Hyaluronic Acid for canine occurs in as little as 5 minutes, this process being described as "Rapid Uptake". Transport of HA occurs through the lymphatic system & cell to cell (CD44) transmission to bones, joints, muscles and connective tissues.
In a study by Carapeda, G. 2016; Canines given Hyaluronic Acid had a "Significant Clinical Improvement" in quality of life & joint mobility. An astonishing 100% in the study experienced improvement due to viscoelastic properties of HA acting as a lubricant, shock absorber, pain reliever as well as it's anti-inflammatory properties.
According to a study published last year by Lee, M. 2019; Canines are unable to maintain enough Hyaluronic Acid (HA) in the Synovial Fluid for proper lubrication of their joints in 90% of older dogs and 20% of younger dogs starting as early as 2 years of age.