Joint Flex Plus · Liquid Joint Support

Fluid joints. Free movement.
One pump a day.

Joint ComfortCartilage SupportSynovial Fluid

Joints move on synovial fluid. Joint Flex Plus supports that fluid and the cartilage it cushions in one daily ounce, top-dressed over the feed you already give.

Each ounce carries 442 mg of hyaluronic acid and 250 mg of silicon as orthosilicic acid, delivered in a proprietary liquid form with up to 99% availability1, 2. Powders & pellets must first break apart, hydrate, & disperse inside a moving gut, which leaves availability as low as 2.5%3.

1Goodridge et al. (2011). doi.org/10.1038/nature100712Balogh et al. (2008). doi.org/10.1021/jf80170293Du et al. (2004). doi.org/10.1002/bdd.392
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Your 2 Gallon Subscription includes
  • 2 Gallons of Joint Flex Plus + 2 pumps
  • 90-Day Money-Back Guarantee
  • Free Equine Nutritionist Consultation
Joint Flex Plus · 2 Gallon
SUGAR FREENo molasses, no filler
USEF / FEIShow compliant
FREE SHIPPINGSame day, ship by 3pm CST
120 DAYSSupply per gallon
Customer reviews

1,178 verified reviews from working barns.

Every discipline. Every level. Real horses on Dr. Peterson’s Protocol.

4.9
★★★★★
out of 5
Based on 1,178 verified reviews
5 stars
87%
4 stars
9%
3 stars
2%
2 stars
1%
1 stars
1%
The absorption gap

What your horse can’t absorb,
your horse can’t use.

Most joint supplements are powders or pellets. They have to dissolve and survive the gut before any of it counts, and most of it never does. Joint Flex Plus is liquid and pre-dispersed, so it’s ready the moment it reaches the gut wall.

Liquid Joint Flex Plus
99%
up to 99% availability
vs
Powders & pellets
2.5%
absorption as low as 2.5%1

Oral bioavailability of administered actives. Powder/pellet figure per Du et al. (2004)1; cited in full in the comparison below.

With most supplements, you pay for a full dose and your horse absorbs a fraction of it. You’re not getting what you think you’re paying for. With Joint Flex Plus, what’s on the label is what reaches your horse.

Orthosilicic acid

Already in solution. The hyaluronan and the silicon arrive in the form the joint can actually use, with no dispersion step in between.

Hyaluronan

High molecular weight, pre-hydrated. No breakdown step to lose it in, which matters for a molecule this large.

The physiology

It’s not marketing. Liquid delivery has been the standard in human medicine for decades. Joint Flex Plus brings it to the barn.

Liquid vs. the rest

Why form is the whole game.

The actives aren’t the differentiator, delivery is. Here’s how liquid stacks up against the pelleted and powdered joint supplements in most feed rooms.

Joint Flex Plus · Liquid
Powders
Pellets
Availability
Up to 99%1,2
3–30%3
3–15%4
Goes to work
On contact
Must dissolve first
Needs to break down first
Dose accuracy
One pump, exact
Scoop & settle
Eats around it
Picky-eater approved
Yes
Hit or miss
Hit or miss
Show safe
USEF / FEI
It depends
It depends
References
1Goodridge et al. (2011). doi.org/10.1038/nature10071
2Balogh et al. (2008). doi.org/10.1021/jf8017029
3Du et al. (2004). doi.org/10.1002/bdd.392
Ingredients

What’s in the jug, why it’s there, and what the science says.

One pump is one ounce. Both actives below are listed at their amount in that ounce, straight off the Product Facts panel.

Measured delivery

One pump, one ounceOff the Product Facts panel

One ounce is a measured dose, not a scoop you level by eye. Every pump delivers 442 mg of hyaluronic acid and 250 mg of silicon as orthosilicic acid, already in solution, so what the panel says is what reaches your horse.

1 oz
per pump

Hyaluronic AcidHyaluronan

Hyaluronan is a normal component of synovial fluid and extracellular matrix, supplied already in solution.

442
mg / oz

SiliconAs orthosilicic acid

Orthosilicic acid is the bioavailable form of silicon, supplied already in solution. Silicon is used in the collagen that cartilage and connective tissue are built from.

250
mg / oz
References
  1. 1Goodridge, H. S., Reyes, C. N., Becker, C. A., et al. (2011). Activation of the innate immune receptor Dectin-1 upon formation of a phagocytic synapse. Nature, 472, 471–475. doi.org/10.1038/nature10071
  2. 2Balogh, L., Polyak, A., Mathe, D., et al. (2008). Absorption, uptake and tissue affinity of high-molecular-weight hyaluronan after oral administration in rats and dogs. Journal of Agricultural and Food Chemistry, 56(22), 10582–10593. doi.org/10.1021/jf8017029
The Protocol

Dr. Peterson’s two-phase protocol

Load with 2 pumps a day for the first 30 days, then settle into a once-daily maintenance pump. Two pumps a day is also recommended through heavy work and show season. Keep it at least two hours apart from NSAIDs.

Day 0Day 30Ongoing
Phase 1 ·
Load / Show Season
2 oz / day
Phase 2 · Maintenance 1 oz / day
≈ 2-month supply per gallon
≈ 4-month supply per gallon
From the barn

Real horses. Here are a few of them.

Real members, real horses, real results. Tag #100XEquine to be featured.

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Dr. Russ Peterson, DVM, Chief Veterinary Officer, 100X Equine
Chief Veterinary Officer

47 years of Equine Medicine, in one jug.

The Veterinary Standard Behind 100X Equine

Dr. Russ Peterson, DVM, MS, DACVSMR, Cert. ISELP brings nearly five decades of equine medicine, sport horse performance, rehabilitation, nutrition, and clinical decision-making to 100X Equine.

As Chief Veterinary Officer, Dr. Peterson helps guide the clinical thinking behind every 100X Equine formula, from ingredient selection to dosing strategy to how those actives are delivered inside the horse.

Joint Flex Plus reflects that standard: hyaluronic acid and silicon as orthosilicic acid, both named on the panel and delivered in a proprietary liquid carrier built to keep them stable and ready for biological contact.

Board-certifiedSports Medicine & RehabilitationEquine NutritionFormulation Science
The 2-part joint system

Fluid and cartilage. One joint.

A joint stays comfortable because fluid cushions it and cartilage holds its shape. Joint Flex Plus supplies building blocks for both in one daily ounce.

01

Synovial fluid

Hyaluronan is the molecule synovial fluid is built on. Joint Flex Plus supplies 442 mg already in solution to support normal joint lubrication and flexibility.

02

Cartilage & connective tissue

Orthosilicic acid supplies silicon, which is used in the collagen that cartilage and connective tissue are built from, the cushion a joint depends on under load.

442 mgHyaluronic acid
250 mgSilicon as orthosilicic acid

Amounts are per one-ounce pump, as listed on the current Product Facts panel. Give at least two hours apart from NSAIDs. See the full panel.

Show-Safe Formula

No prohibited substances. Joint Flex Plus is USEF and FEI compliant, so it stays legal for horses competing under both rule sets.

90-Day Money-Back Guarantee

Feed it daily for 90 days. If you don’t see the difference, we refund you, with free shipping on every order.

Subscribe & Save

Put any protocol on auto-delivery and lock in a better price on every order. Pause, skip, swap, or change your delivery dates anytime, fully in your control.

Still deciding

Questions, answered.

Most owners report a change in movement and comfort within the first 30 days, and some sooner. Joint Flex Plus is daily, long-term joint and cartilage support, not a quick fix. If you don’t see the difference, you’re backed by our 90-day money-back guarantee.
Joint Flex Plus is a palatable liquid that coats the existing ration, so most horses accept it with no fuss. If yours is especially fussy, our equine nutritionists help you transition, included free with every order.
Your Joint Flex Plus subscription is fully flexible. Manage it anytime in your account or by SMS: pause, change delivery dates, or cancel with no fees and no phone tree.
Yes. USEF and FEI compliant. No prohibited substances, so it’s cleared for horses showing under both rule sets.
The full system

Pair Joint Flex Plus with another protocol.

Stack more and save up to 40% off. Adjust anytime.

Put your horse on the protocol.

Start with Joint Flex Plus. Synovial fluid and cartilage support in one pump a day, built on Dr. Peterson’s 47+ years of equine medicine.

Start with Joint Flex Plus

Feed it daily for 90 days. If you don’t see the difference,
we refund you.