Fluid joints. Free movement.
One pump a day.
Joint ComfortCartilage SupportSynovial Fluid
Joints move on synovial fluid. Joint Flex Plus supports that fluid and the cartilage it cushions in one daily ounce, top-dressed over the feed you already give.
Each ounce carries 442 mg of hyaluronic acid and 250 mg of silicon as orthosilicic acid, delivered in a proprietary liquid form with up to 99% availability1, 2. Powders & pellets must first break apart, hydrate, & disperse inside a moving gut, which leaves availability as low as 2.5%3.
- ✓2 Gallons of Joint Flex Plus + 2 pumps
- ✓90-Day Money-Back Guarantee
- ✓Free Equine Nutritionist Consultation
1,178 verified reviews from working barns.
Every discipline. Every level. Real horses on Dr. Peterson’s Protocol.
What your horse can’t absorb,
your horse can’t use.
Most joint supplements are powders or pellets. They have to dissolve and survive the gut before any of it counts, and most of it never does. Joint Flex Plus is liquid and pre-dispersed, so it’s ready the moment it reaches the gut wall.
Oral bioavailability of administered actives. Powder/pellet figure per Du et al. (2004)1; cited in full in the comparison below.
With most supplements, you pay for a full dose and your horse absorbs a fraction of it. You’re not getting what you think you’re paying for. With Joint Flex Plus, what’s on the label is what reaches your horse.
Already in solution. The hyaluronan and the silicon arrive in the form the joint can actually use, with no dispersion step in between.
High molecular weight, pre-hydrated. No breakdown step to lose it in, which matters for a molecule this large.
It’s not marketing. Liquid delivery has been the standard in human medicine for decades. Joint Flex Plus brings it to the barn.
Why form is the whole game.
The actives aren’t the differentiator, delivery is. Here’s how liquid stacks up against the pelleted and powdered joint supplements in most feed rooms.
What’s in the jug, why it’s there, and what the science says.
One pump is one ounce. Both actives below are listed at their amount in that ounce, straight off the Product Facts panel.
One pump, one ounceOff the Product Facts panel
One ounce is a measured dose, not a scoop you level by eye. Every pump delivers 442 mg of hyaluronic acid and 250 mg of silicon as orthosilicic acid, already in solution, so what the panel says is what reaches your horse.
Hyaluronic AcidHyaluronan
Hyaluronan is a normal component of synovial fluid and extracellular matrix, supplied already in solution.
SiliconAs orthosilicic acid
Orthosilicic acid is the bioavailable form of silicon, supplied already in solution. Silicon is used in the collagen that cartilage and connective tissue are built from.
- 1Goodridge, H. S., Reyes, C. N., Becker, C. A., et al. (2011). Activation of the innate immune receptor Dectin-1 upon formation of a phagocytic synapse. Nature, 472, 471–475. doi.org/10.1038/nature10071
- 2Balogh, L., Polyak, A., Mathe, D., et al. (2008). Absorption, uptake and tissue affinity of high-molecular-weight hyaluronan after oral administration in rats and dogs. Journal of Agricultural and Food Chemistry, 56(22), 10582–10593. doi.org/10.1021/jf8017029
Dr. Peterson’s two-phase protocol
Load with 2 pumps a day for the first 30 days, then settle into a once-daily maintenance pump. Two pumps a day is also recommended through heavy work and show season. Keep it at least two hours apart from NSAIDs.
Real horses. Here are a few of them.
Real members, real horses, real results. Tag #100XEquine to be featured.




2



4



2


2
2

2


2
3



2


2

47 years of Equine Medicine, in one jug.
The Veterinary Standard Behind 100X Equine
Dr. Russ Peterson, DVM, MS, DACVSMR, Cert. ISELP brings nearly five decades of equine medicine, sport horse performance, rehabilitation, nutrition, and clinical decision-making to 100X Equine.
As Chief Veterinary Officer, Dr. Peterson helps guide the clinical thinking behind every 100X Equine formula, from ingredient selection to dosing strategy to how those actives are delivered inside the horse.
Joint Flex Plus reflects that standard: hyaluronic acid and silicon as orthosilicic acid, both named on the panel and delivered in a proprietary liquid carrier built to keep them stable and ready for biological contact.
Fluid and cartilage. One joint.
A joint stays comfortable because fluid cushions it and cartilage holds its shape. Joint Flex Plus supplies building blocks for both in one daily ounce.
Synovial fluid
Hyaluronan is the molecule synovial fluid is built on. Joint Flex Plus supplies 442 mg already in solution to support normal joint lubrication and flexibility.
Cartilage & connective tissue
Orthosilicic acid supplies silicon, which is used in the collagen that cartilage and connective tissue are built from, the cushion a joint depends on under load.
Amounts are per one-ounce pump, as listed on the current Product Facts panel. Give at least two hours apart from NSAIDs. See the full panel.
Show-Safe Formula
No prohibited substances. Joint Flex Plus is USEF and FEI compliant, so it stays legal for horses competing under both rule sets.
90-Day Money-Back Guarantee
Feed it daily for 90 days. If you don’t see the difference, we refund you, with free shipping on every order.
Subscribe & Save
Put any protocol on auto-delivery and lock in a better price on every order. Pause, skip, swap, or change your delivery dates anytime, fully in your control.
Questions, answered.
Pair Joint Flex Plus with another protocol.
Stack more and save up to 40% off. Adjust anytime.
Put your horse on the protocol.
Start with Joint Flex Plus. Synovial fluid and cartilage support in one pump a day, built on Dr. Peterson’s 47+ years of equine medicine.
Start with Joint Flex PlusFeed it daily for 90 days. If you don’t see the difference,
we refund you.