Joint, Soft Tissue & Bone
Osteo-MAX
Bone density, joint integrity, and recovery for hard-working and aging horses.
$175.16
Osteo-MAX · Denim, Day 90
Common Questions
One pump is one ounce, top-dressed on feed. Load at 2 pumps a day: 30 days for soft tissue, 30 to 60 days for bone. Then hold at 1 pump a day for maintenance. The calibrated pump makes every dose exact.
A gallon is 128 pumps: about 4 months at the maintenance dose, or about 2 months while you’re loading at 2 pumps a day.
Osteo-MAX is a palatable liquid that coats the existing ration, so most horses accept it with no fuss. If yours is especially fussy, our equine nutritionists help you transition, included free with every order.
Yes, and most barns do. Gut X handles absorption and gut health, Osteo-MAX handles the structure. Together they are The Foundation Stack, our most popular bundle. Stacking them together saves 26%. Learn more →
Anytime. Manage everything in your account or by SMS: pause, change delivery dates, or cancel with no fees and no phone tree.
Most owners report a change in movement, comfort, and willingness to work within the first 30 days, and some sooner. Bone remodels on a longer clock than soft tissue, which is why the loading phase runs 30 to 60 days for bone support.
Osteo-MAX supplies structural nutrients that hay and grain do not provide in this form or amount: silicon as orthosilicic acid, hyaluronic acid, vitamin K2 and D3, and the amino acids collagen is built from. Fed daily, they support bone formation, joint lubrication, and connective tissue repair over time.
And if you don’t see the difference, you’re backed by our 90-day money-back guarantee.
Osteo-MAX · 3-in-1 Liquid Support
Strong bones. Sound joints.
One pump a day.
Bone SupportJoint ComfortTendon & Ligament Support
Bone, joint, and connective tissue work as one system. Osteo-MAX supports all three in one daily ounce, top-dressed over the feed you already give.
Each ounce carries silicon as orthosilicic acid, hyaluronic acid, vitamins K2 and D3, and a 6,975 mg amino acid blend, delivered in a proprietary liquid form with up to 99% availability1, 2. Powders & pellets must first break apart, hydrate, & disperse inside a moving gut, which leaves availability as low as 2.5%3.
1Goodridge et al. (2011). doi.org/10.1038/nature100712Balogh et al. (2008). doi.org/10.1021/jf80170293Du et al. (2004). doi.org/10.1002/bdd.392
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90-day money-back
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Your 1 Gallon Subscription includes
- ✓1 Gallon of Osteo-MAX + 1 pump
- ✓90-Day Money-Back Guarantee
- ✓Free Equine Nutritionist Consultation
Customer reviews
8,837 verified reviews from working barns.
Every discipline. Every level. Real horses on Dr. Peterson’s Protocol.
4.9
★★★★★
out of 5
Based on 8,837 verified reviews
90 Days · The Peterson Protocol
This is what doing well looks like.
Denim, 90 days apart. Same horse, one pump a day.
Denim · 90 days on Osteo-MAX
Shot in March at the start of the protocol and again in June. One pump of Osteo-MAX a day through the spring.
Day 0
Day 0. March, the day the protocol started.
Day 90
Day 90. June, 90 days on one pump a day.
The absorption gap
What your horse can’t absorb,
your horse can’t use.
Most joint and bone supplements are powders or pellets. They have to dissolve and survive the gut before any of it counts, and most of it never does. Osteo-MAX is liquid and pre-dispersed, so it’s ready the moment it reaches the gut wall.
Liquid Osteo-MAX
vs
99%
up to 99% availability
Powders & pellets
2.5%
absorption as low as 2.5%1
Oral bioavailability of administered actives. Powder/pellet figure per Du et al. (2004)1; cited in full above.
With most supplements, you pay for a full dose and your horse absorbs a fraction of it. You’re not getting what you think you’re paying for. With Osteo-MAX, what’s on the label is what reaches your horse.
Orthosilicic acid
The bioavailable form of silicon. Already in solution, so it arrives in the form the bone-building cells can actually use.
Hyaluronan
High molecular weight, pre-hydrated. No breakdown step to lose it in, which matters for a molecule this large.
The physiology
It’s not marketing. Liquid delivery has been the standard in human medicine for decades. Osteo-MAX brings it to the barn.
Liquid vs. the rest
Why form is the whole game.
The actives aren’t the differentiator, delivery is. Here’s how liquid stacks up against the pelleted and powdered joint supplements in most feed rooms.
Osteo-MAX · Liquid
Powders
Pellets
Availability
Up to 99%1,2
3–30%3
3–15%4
Goes to work
On contact
Must dissolve first
Needs to break down first
Dose accuracy
One pump, exact
Scoop & settle
Eats around it
Picky-eater approved
Yes
Hit or miss
Hit or miss
Show safe
USEF / FEI
It depends
It depends
References
1Goodridge et al. (2011). doi.org/10.1038/nature10071
2Balogh et al. (2008). doi.org/10.1021/jf8017029
3Du et al. (2004). doi.org/10.1002/bdd.392
4Raval et al. (2025). doi.org/10.2174/0124681873309964240521074809
Ingredients
What’s in the jug, why it’s there, and what the science says.
One pump is one ounce. Every active below is listed at its amount in that ounce, with the published research it rests on. The amino acid blend is proprietary, listed at its 6,975 mg total.
The system
Liquid SystemProprietary liquid carrier
A pre-dispersed liquid suspension designed to support serving consistency and reduce the dry-form disintegration step.1, 2
up to
99%
availability
Amino Acid BlendGlycine, lysine, phenylalanine, ornithine, arginine, proline, threonine, serine
Supplies amino acids used in collagen and whole-body protein synthesis, including building blocks found throughout tendon, ligament, and connective tissue.3–8
6,975
mg / oz
Siliconas Orthosilicic Acid
Orthosilicic acid is a bioavailable form of silicon. Published work links it to type I collagen synthesis, osteoblast differentiation, bone-formation markers, and regulation of osteoclast activity.9–13
430
mg / oz
Hyaluronic AcidHyaluronan
Hyaluronan is a normal component of synovial fluid and extracellular matrix. Oral HA has absorption, tissue-distribution, and clinical literature, including direct equine research.14–17
150
mg / oz
Vitamin K2 (MK7)Menaquinone-7
Supports activation of vitamin K-dependent proteins such as osteocalcin and matrix Gla protein, which are involved in bone mineralization and regulation of soft-tissue calcification.18–22
50
mg / oz
BiotinVitamin B7
Biotin has direct equine evidence for supporting hoof horn quality. Because new hoof horn must grow out, visible changes are expected over months, not days.23–26
15
mg / oz
Vitamin D3Cholecalciferol
Supports calcium and phosphorus homeostasis and normal bone metabolism. Total intake from the complete ration should be considered.27–29
5,000
iu / oz
References
- 1Goodridge, H. S., Reyes, C. N., Becker, C. A., et al. (2011). Activation of the innate immune receptor Dectin-1 upon formation of a phagocytic synapse. Nature, 472, 471–475. doi.org/10.1038/nature10071
- 2Balogh, L., Polyak, A., Mathe, D., et al. (2008). Absorption, uptake and tissue affinity of high-molecular-weight hyaluronan after oral administration in rats and dogs. Journal of Agricultural and Food Chemistry, 56(22), 10582–10593. doi.org/10.1021/jf8017029
- 3Graham-Thiers, P. M., & Kronfeld, D. S. (2005). Amino acid supplementation improves muscle mass in aged and young horses. Journal of Animal Science, 83(12), 2783–2788. academic.oup.com
- 4Van den Hoven, R., Bauer, A., Hackl, S., et al. (2011). Changes in potential markers of muscle-cell degradation in exercised horses supplemented with a protein and amino acid mixture. Journal of Animal Physiology and Animal Nutrition. doi.org/10.1111/j.1439-0396.2010.01097.x
- 5Tanner, S. L., Wagner, A. L., Digianantonio, R. N., et al. (2014). Dietary crude protein intake influences rates of whole-body protein synthesis in weanling horses. The Veterinary Journal. sciencedirect.com
- 6Latham, C. M., Wagner, A. L., et al. (2019). Effects of dietary amino acid supplementation on measures of whole-body and muscle protein metabolism in aged horses. Journal of Animal Physiology and Animal Nutrition. doi.org/10.1111/jpn.12992
- 7Mastellar, S. L., Coleman, R. J., & Urschel, K. L. (2016). Controlled trial of whole body protein synthesis and plasma amino acid concentrations in yearling horses fed graded amounts of lysine. The Veterinary Journal. sciencedirect.com
- 8Mastellar, S. L., Moffet, A., Harris, P. A., & Urschel, K. L. (2016). Effects of threonine supplementation on whole-body protein synthesis and plasma metabolites in growing and mature horses. The Veterinary Journal. sciencedirect.com
- 9Pritchard, A. (2020). The role alterations in dietary calcium and silicon balance play on bone and cartilage in horses and poultry. Graduate thesis. proquest.com
- 10Nielsen, B. D. (2023). A review of three decades of research dedicated to making equine bones stronger: implications for horses and humans. Animals, 13(5), 789. doi.org/10.3390/ani13050789
- 11Logan, A. A., & Nielsen, B. D. (2021). Training young horses: the science behind the benefits. Animals, 11(2), 463. doi.org/10.3390/ani11020463
- 12Fowler, A. L., Pyles, M. B., Hayes, S. H., et al. (2022). Effect of weight change on markers of bone turnover and phosphorus excretion. Journal of Equine Veterinary Science. sciencedirect.com
- 13Saastamoinen, M., & Valtonen, S. S. E. (2020). The effect of diet composition on the digestibility and fecal excretion of phosphorus in horses: a potential risk of phosphorus leaching? Animals. go.gale.com
- 14Carmona, J. U., Argüelles, D., Deulofeu, R., et al. (2009). Effect of the administration of an oral hyaluronan formulation on clinical and biochemical parameters in young horses with osteochondrosis. Veterinary and Comparative Orthopaedics and Traumatology. doi.org/10.3415/VCOT-09-01-0001
- 15Niemelä, T. M., Tulamo, R. M., Aaltonen, K., et al. (2018). Changes in biomarkers in equine synovial fluid two weeks after intra-articular hyaluronan treatment: a randomised double-blind clinical trial. BMC Veterinary Research. doi.org/10.1186/s12917-018-1512-2
- 16Niemelä, T. M., Tulamo, R. M., Carmona, J. U., et al. (2019). Evaluation of the effect of experimentally induced cartilage defect and intra-articular hyaluronan on synovial fluid biomarkers in intercarpal joints of horses. Acta Veterinaria Scandinavica. doi.org/10.1186/s13028-019-0460-6
- 17da Silva Xavier, A. A., da Rosa, P. P., et al. (2021). An assessment of the effectiveness of hyaluronic acid and polyacrylamide hydrogel in horses with osteoarthritis: systematic review and network meta-analysis. Research in Veterinary Science. sciencedirect.com
- 18National Research Council. (2007). Nutrient Requirements of Horses, 6th revised edition. National Academies Press. doi.org/10.17226/11653
- 19Mandatori, D., Pelusi, L., Schiavone, V., et al. (2021). The dual role of vitamin K2 in bone-vascular crosstalk: opposite effects on bone loss and vascular calcification. Nutrients, 13(4), 1222. doi.org/10.3390/nu13041222
- 20Atkins, G. J., Welldon, K. J., Wijenayaka, A. R., et al. (2009). Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by gamma-carboxylation-dependent and independent mechanisms. American Journal of Physiology-Cell Physiology. doi.org/10.1152/ajpcell.00216.2009
- 21Yilmaz, I. C., Güler, T., Ekmen, E. G., & Özçelik, M. (2026). The effects of boron mineral on performance, bone and mineral metabolism in Purebred Arabian foals. Biological Trace Element Research. doi.org/10.1007/s12011-026-05138-x
- 22Vervuert, I., & Stratton-Phelps, M. (2021). The safety and efficacy in horses of certain nutraceuticals that claim to have health benefits. Veterinary Clinics of North America: Equine Practice. vetequine.theclinics.com
- 23Geyer, H., & Schulze, J. (1994). The long-term influence of biotin supplementation on hoof horn quality in horses. Schweizer Archiv für Tierheilkunde, 136, 137–149.
- 24Josseck, H., Zenker, W., & Geyer, H. (1995). Hoof horn abnormalities in Lipizzaner horses and the effect of dietary biotin on macroscopic aspects of hoof horn quality. Equine Veterinary Journal, 27(3), 175–182. doi.org/10.1111/j.2042-3306.1995.tb03060.x
- 25Zenker, W., Josseck, H., & Geyer, H. (1995). Histological and physical assessment of poor hoof horn quality in Lipizzaner horses and a therapeutic trial with biotin and a placebo. Equine Veterinary Journal, 27(3), 183–191. doi.org/10.1111/j.2042-3306.1995.tb03061.x
- 26Burns, T. A. (2021). Feeding the foot: nutritional influences on equine hoof health. Veterinary Clinics of North America: Equine Practice. vetequine.theclinics.com
- 27Dittmer, K. E., & Thompson, K. G. (2011). Vitamin D metabolism and rickets in domestic animals: a review. Veterinary Pathology, 48(2), 389–407. doi.org/10.1177/0300985810375240
- 28Robles, M., Hammer, C., Staniar, W. B., et al. (2021). Nutrition of broodmares. Veterinary Clinics of North America: Equine Practice. vetequine.theclinics.com
- 29Robles, M., Gautier, C., Mendoza, L., et al. (2017). Maternal nutrition during pregnancy affects testicular and bone development, glucose metabolism and response to overnutrition in weaned horses up to two years. PLoS ONE, 12(1), e0169295. doi.org/10.1371/journal.pone.0169295
The Protocol
Dr. Peterson’s two-phase protocol
Load with 2 pumps a day: 30 days for soft tissue, 30 to 60 days for bone. Then settle into a once-daily maintenance pump. Two pumps a day is also recommended through heavy work, rehab, and show season.
Day 0Day 30-60Ongoing
≈ 2-month supply per gallon
≈ 4-month supply per gallon
From the barn
84,000 horses. Here are a few of them.
Real members, real horses, real results. Tag #100XEquine to be featured.
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5
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Chief Veterinary Officer
47 years of Equine Medicine, in one jug.
The Veterinary Standard Behind 100X Equine
Dr. Russ Peterson, DVM, MS, DACVSMR, Cert. ISELP brings nearly five decades of equine medicine, sport horse performance, rehabilitation, nutrition, and clinical decision-making to 100X Equine.
As Chief Veterinary Officer, Dr. Peterson helps guide the clinical thinking behind every 100X Equine formula, from ingredient selection to dosing strategy to how those actives are delivered inside the horse.
Osteo-MAX reflects that standard: silicon as orthosilicic acid, hyaluronic acid, vitamins K2 and D3, and a 6,975 mg amino acid blend, all named on the panel and delivered in a proprietary liquid carrier built to keep them stable and ready for biological contact.
Board-certifiedSports Medicine & RehabilitationEquine NutritionFormulation Science
The 3-part structural formula
Three structures. One movement system.
Bone, joints, tendons, and ligaments work together as one movement system. Many supplement programs address them separately. Osteo-MAX brings their nutritional support together in one daily ounce.
01
Bone
Orthosilicic acid, vitamin K2, and vitamin D3 support the collagen framework of bone, normal mineral metabolism, and ongoing bone remodeling.
02
Joint
Hyaluronan is a natural component of synovial fluid and extracellular matrix. Osteo-MAX supplies 150 mg already in solution to support normal joint lubrication and function.
03
Tendon & ligament
A 6,975 mg amino acid blend supplies glycine, lysine, proline, and other amino acids used in collagen and protein synthesis, supporting normal maintenance and turnover of tendons, ligaments, fascia, and other connective tissues. Orthosilicic acid supports that same collagen synthesis.
430 mgSilicon as orthosilicic acidPlus vitamin K2 and vitamin D3
150 mgHyaluronic acid
6,975 mgAmino acid blend
Additional structural support Also supplies biotin to support hoof horn quality. Amounts are per one-ounce pump, as listed on the current Product Facts panel. See the full panel.
Show-Safe Formula
No prohibited substances. Osteo-MAX is USEF and FEI compliant, so it stays legal for horses competing under both rule sets.
90-Day Money-Back Guarantee
Feed it daily for 90 days. If you don’t see the difference, we refund you, with free shipping on every order.
Subscribe & Save
Put any protocol on auto-delivery and lock in a better price on every order. Pause, skip, swap, or change your delivery dates anytime, fully in your control.
Still deciding
Questions, answered.
Most owners report a change in movement and comfort within the first 30 days, and some sooner. Osteo-MAX is daily, long-term bone, joint, and connective tissue support, not a quick fix. If you don’t see the difference, you’re backed by our 90-day money-back guarantee.
Osteo-MAX is a palatable liquid that coats the existing ration, so most horses accept it with no fuss. If yours is especially fussy, our equine nutritionists help you transition, included free with every order.
Your Osteo-MAX subscription is fully flexible. Manage it anytime in your account or by SMS: pause, change delivery dates, or cancel with no fees and no phone tree.
Yes. USEF and FEI compliant. No prohibited substances, so it’s cleared for horses showing under both rule sets.
The full system
Pair Osteo-MAX with another protocol.
Stack more and save up to 40% off. Adjust anytime.
Gut & Immune
Gut X
Liquid gut health and immune support, the foundation every other protocol builds on.
$100.64
Mobility
Joint Flex Plus
Everyday joint flexibility and comfort for performance and senior horses.
$100.64
Topline & Muscle
Amino-MAX
Amino acids for topline, muscle, and a stronger frame under saddle.
$118.45
Electrolytes + Creatine
Hydra-MAX
Electrolyte and hydration support for sweat, travel, and hot, hard days.
$112.22
Calm & Focus
Max Calm
Liquid calming support for focus and rideability, without the dullness.
$100.64
Put your horse on the protocol.
Start with Osteo-MAX. Bone, joint, and connective tissue support in one pump a day, built on Dr. Peterson’s 47+ years of equine medicine.
Start with Osteo-MAXFeed it daily for 90 days. If you don’t see the difference,
we refund you.
Osteo-MAX
★★★★★4.98,837 reviews84,000+ horses
Liquid joint, soft tissue and bone support. Built for horses in hard work and horses getting older.
Subscriptions from
$1.45/day
Save up to 39% Today
- Joint comfort & mobilityEases stiffness and keeps joints moving.
- Bone densitySupports strong bone under work and age.
- Soft-tissue recoveryHelps tendons and ligaments bounce back.
Orthosilicic acidHyaluronanVit K2 (MK7)
Free shipping
90-day money-back
FREE delivery —. Order within —
Product details
Every amount is on the label, to the milligram, with the peer-reviewed work behind it listed below. The amino blend is proprietary by ratio, and its total is still stated.
See the full labelThe systemLiquid SystemProprietary liquid carrier99%availability
A pre-dispersed liquid suspension designed to support serving consistency and reduce the dry-form disintegration step, with up to 99%1,2 availability.
Amino Acid BlendGlycine, lysine, phenylalanine, ornithine, arginine, proline, threonine, serine6,975mg / oz
Supplies amino acids used in collagen and whole-body protein synthesis, including building blocks found throughout tendon, ligament and connective tissue.3–8
Siliconas Orthosilicic Acid430mg / oz
Orthosilicic acid is a bioavailable form of silicon. Published work links it to type I collagen synthesis, osteoblast differentiation, bone-formation markers and the regulation of osteoclast activity.9–13
Hyaluronic AcidHyaluronan150mg / oz
Hyaluronan is a normal component of synovial fluid and extracellular matrix. Oral HA has absorption, tissue-distribution and clinical literature, including direct equine research.14–17
Vitamin K2 (MK7)Menaquinone-750mg / oz
Supports activation of vitamin K-dependent proteins such as osteocalcin and matrix Gla protein, which are involved in bone mineralization and the regulation of soft-tissue calcification.18–22
BiotinVitamin B715mg / oz
Biotin has direct equine evidence for supporting hoof horn quality. Because new hoof horn has to grow out, visible changes are expected over months, not days.23–26
Vitamin D3Cholecalciferol5,000iu / oz
Supports calcium and phosphorus homeostasis and normal bone metabolism. Total intake from the complete ration should be considered.27–29
References
1Goodridge et al. (2011). 10.1038/nature10071
2Balogh et al. (2008). 10.1021/jf8017029
3Graham-Thiers & Kronfeld (2005). Oxford Academic
4Van den Hoven et al. (2011). 10.1111/j.1439-0396.2010.01097.x
5Tanner et al. (2014). ScienceDirect
6Latham et al. (2019). 10.1111/jpn.12992
7Mastellar et al. (2016). ScienceDirect
8Mastellar et al. (2016). ScienceDirect
9Pritchard (2020). ProQuest
10Nielsen (2023). 10.3390/ani13050789
11Logan & Nielsen (2021). 10.3390/ani11020463
12Fowler et al. (2022). ScienceDirect
13Saastamoinen & Valtonen (2020). Gale
14Carmona et al. (2009). 10.3415/VCOT-09-01-0001
15Niemelä et al. (2018). 10.1186/s12917-018-1512-2
16Niemelä et al. (2019). 10.1186/s13028-019-0460-6
17da Silva Xavier et al. (2021). ScienceDirect
18National Research Council (2007). 10.17226/11653
19Mandatori et al. (2021). 10.3390/nu13041222
20Atkins et al. (2009). 10.1152/ajpcell.00216.2009
21Yilmaz et al. (2026). 10.1007/s12011-026-05138-x
22Vervuert & Stratton-Phelps (2021). Vet Clinics Equine
23Geyer & Schulze (1994). Schweizer Archiv für Tierheilkunde 136, 137–149
24Josseck et al. (1995). 10.1111/j.2042-3306.1995.tb03060.x
25Zenker et al. (1995). 10.1111/j.2042-3306.1995.tb03061.x
26Burns (2021). Vet Clinics Equine
27Dittmer & Thompson (2011). 10.1177/0300985810375240
28Robles et al. (2021). Vet Clinics Equine
29Robles et al. (2017). 10.1371/journal.pone.0169295
Dr. Peterson’s two-phase protocol. Load with 2 pumps a day: 30 days for soft tissue, 30 to 60 days for bone. Then settle into 1 pump a day.
- Pump it straight over the existing ration. The liquid coats the feed, so picky eaters take it without a fight.
- One gallon is 128 maintenance doses, up to a 4 month supply for one horse.
- On the two-pump loading dose a gallon runs about 2 months, which is why a first order is usually 2 gallons.
Most owners notice easier movement in 2 to 3 weeks. Bone and soft tissue remodel slowly, so gains keep building through month 6.
- Day 0 to 60, the loading dose is doing the work.
- After that, one pump a day holds it.
- Hoof horn has to grow out, so the biotin changes show over months, not weeks.
The comparison
Why form is the whole game.
The actives are not the differentiator, delivery is. Here is how liquid stacks up against the dry supplements in most feed rooms.
Osteo-MAX liquidPowder / pellet
Delivery form
Pre-dispersed liquid, suspendedDry particles, must hydrate
Availability
Up to 99%1,2As low as 2.5%3
Dose accuracy
One pump, exactScoop, settles and separates
Goes to work
On contactMust break down first
Dose consistency
All seven actives, to the milligram, every pumpVaries with settling
References1 Goodridge et al. (2011). 10.1038/nature10071
2 Balogh et al. (2008). 10.1021/jf8017029
3 Du et al. (2004). 10.1002/bdd.392
2 Balogh et al. (2008). 10.1021/jf8017029
3 Du et al. (2004). 10.1002/bdd.392
Why liquid
Ready the moment it hits the gut.
Osteo-MAX is delivered in a proprietary liquid form with up to 99% availability1,2. Powders and pellets must first break apart, hydrate and disperse into usable surface area inside a moving gut, a slow, variable process that leaves availability as low as 2.5%3.
1Goodridge et al. (2011)2Balogh et al. (2008)3Du et al. (2004)
90 Days · The Peterson Protocol
This is what doing well looks like.
Denim, 90 days apart. Same horse, same barn, one protocol.
Who formulates it
Dr. Russ Peterson, DVM
MS · DACVSMR · Cert. ISELP
Chief Veterinary Officer
Chief Veterinary Officer
Nearly five decades of equine medicine, sport horse performance, rehabilitation and nutrition. Osteo-MAX reflects that standard: seven actives with equine literature behind them, every amount on the label, and a liquid carrier built to keep them stable and dispersed.
Start the protocol
One pump a day. Feed it for 90 days, and if your horse is not doing better, we refund you.
Subscribe & SaveFree shipping. Pause, change or cancel anytime.