Osteo-MAX + Gut X · The Foundation Stack

Bone, joint & connective tissue,
on a gut that can use it.

Bone & Joint SupportConnective TissueGut & Immune Support

Osteo-MAX is bone, joint & connective tissue support. Gut X supports gut health & triggers immune response. Fed together they cover the two halves of the same problem: what you put in, and what your horse can actually take up.

Both are delivered in a proprietary liquid form with up to 99% availability1, 2. Powders & pellets must first break apart, hydrate, & disperse inside a moving gut, a slow, variable process that leaves availability as low as 2.5%3.

1Goodridge et al. (2011). doi.org/10.1038/nature100712Balogh et al. (2008). doi.org/10.1021/jf80170293Du et al. (2004). doi.org/10.1002/bdd.392
★★★★★ 4.9 / 5 5,679 reviews 112,000+ horses on product
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Your one-time order includes
  • ✓90-Day Money-Back Guarantee
  • ✓Free Equine Nutritionist Consultation
  • ✓Up to a 4 month supply per gallon (1 gallon Osteo-MAX + 1 gallon Gut X + 2 pumps)
✓$20,000 Colic Surgery Coverage Program is a Subscription benefit. One-time orders ship without Colic Surgery Coverage. Switch to Subscribe to include it.
✓Subscriber pricing saves 20% on every delivery.
Osteo-MAX + Gut X · 1 + 1 Gallon
112,000+Horses supported
USEF / FEIShow compliant
FREE SHIPPINGSame day, ship by 3pm CST
$20,000Colic coverage on subscription
Customer reviews

5,679 verified reviews from working barns.

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Real results. Real reviews. Verified by horse owners on Dr. Peterson’s Protocol.

4.9
★★★★★
out of 5
Based on 5,679 verified reviews
5 stars
96%
4 stars
4%
3 stars
<1%
2 stars
<1%
1 stars
<1%
★★★★★
“I’ve been AMAZED with both Osteo-MAX + Gut X. After only 4 weeks of using Osteo-MAX the x-rays have shown significant improvement already. It’s so wonderful to have a happy, healthy horse again!”
Julie H. ✓ Verified member
Ingredients

What’s in the Gut X jug, why it’s there, and what the science says.

Every active ingredient in Gut X is at the upper end of its peer-reviewed efficacy range5, 6, 9, 10. No undisclosed dosing. Every gram is named, sourced, and dosed for clinical effect.

The system

Liquid SystemProprietary liquid carrier

The proprietary carrier stabilizes, suspends, and pre-disperses every active before feeding, supporting uniform dosing and up to 99%2, 7, 8 availability, while powders and pellets can assimilate as low as 2.5%1.

up to
99%
availability

Beta Glucanβ-1,3 / 1,6 glucan

β-1,3 / 1,6 glucan, a soluble fiber that works on contact with the gut’s immune tissue, supporting a healthy stomach lining and immune response.2, 4, 10

196
mg / oz

Hyaluronic AcidSodium hyaluronate

A high molecular weight form of hyaluronic acid that works on contact, helping form a hydrated, protective coating across the stomach and small intestine.7, 8, 10, 11

200
mg / oz
References
  1. 1Du, J., White, N., & Eddington, N. D. (2004). Bioavailability of glucosamine and chondroitin sulfate in horses. Biopharmaceutics & Drug Disposition, 25(3), 109–116. doi.org/10.1002/bdd.392
  2. 2Goodridge, H. S., et al. (2011). Dectin-1 activation through beta-glucan immune receptor signaling. Nature, 472, 471–475. doi.org/10.1038/nature10071
  3. 3Goodridge, H. S., et al. (2009). β-glucan recognition by the innate immune system. Immunological Reviews, 230, 38–50. doi.org/10.1111/j.1600-065X.2009.00793.x
  4. 4Tsoni, S. V., & Brown, G. D. (2008). β-glucans and Dectin-1 immune receptor signaling. Annals of the New York Academy of Sciences, 1143, 45–60. doi.org/10.1196/annals.1443.019
  5. 5Picetti, et al. (2021). Oral β-glucan and complement activity in horses. Veterinary World, 14(4), 835–840. doi.org/10.14202/vetworld.2021.835-840
  6. 6Lacerenza, et al. (2024). β-glucan supplementation and LPS-induced endotoxemia in horses. Animals, 14(3), 474. doi.org/10.3390/ani14030474
  7. 7Balogh, L., et al. (2008). Absorption and tissue affinity of high-molecular-weight hyaluronan after oral administration. Journal of Agricultural and Food Chemistry, 56(22), 10582–10593. doi.org/10.1021/jf8017029
  8. 8Sammarco, et al. (2019). Hyaluronan and intestinal mucosal healing. Cells, 8(9), 1074. doi.org/10.3390/cells8091074
  9. 9Slovis, N. M. (2017). Polysaccharide treatment reduces gastric ulceration in active horses. Journal of Equine Veterinary Science, 50, 116–120. doi.org/10.1016/j.jevs.2016.11.011
  10. 10Andrews, et al. (2025). Hyaluronan + β-glucan and gastric ulcer scores in horses. Equine Veterinary Education, 1–10. doi.org/10.1111/eve.70009
  11. 11Misra, S., et al. (2015). Interactions between hyaluronan and its receptors (CD44, RHAMM) regulate inflammation. Frontiers in Immunology, 6, 201. doi.org/10.3389/fimmu.2015.00201
Ingredients

What’s in the Osteo-MAX jug, why it’s there, and what the science says.

One pump is one ounce. Every active below is listed at its amount in that ounce, with the published research it rests on. The amino acid blend is proprietary, listed at its 6,975 mg total.

The system

Liquid SystemProprietary liquid carrier

A pre-dispersed liquid suspension designed to support serving consistency and reduce the dry-form disintegration step.1, 2

up to
99%
availability

Amino Acid BlendGlycine, lysine, phenylalanine, ornithine, arginine, proline, threonine, serine

Supplies amino acids used in collagen and whole-body protein synthesis, including building blocks found throughout tendon, ligament, and connective tissue.3–8

6,975
mg / oz

Siliconas Orthosilicic Acid

Orthosilicic acid is a bioavailable form of silicon. Published work links it to type I collagen synthesis, osteoblast differentiation, bone-formation markers, and regulation of osteoclast activity.9–13

430
mg / oz

Hyaluronic AcidHyaluronan

Hyaluronan is a normal component of synovial fluid and extracellular matrix. Oral HA has absorption, tissue-distribution, and clinical literature, including direct equine research.14–17

150
mg / oz

Vitamin K2 (MK7)Menaquinone-7

Supports activation of vitamin K-dependent proteins such as osteocalcin and matrix Gla protein, which are involved in bone mineralization and regulation of soft-tissue calcification.18–22

50
mg / oz

BiotinVitamin B7

Biotin has direct equine evidence for supporting hoof horn quality. Because new hoof horn must grow out, visible changes are expected over months, not days.23–26

15
mg / oz

Vitamin D3Cholecalciferol

Supports calcium and phosphorus homeostasis and normal bone metabolism. Total intake from the complete ration should be considered.27–29

5,000
iu / oz
References
  1. 1Goodridge, H. S., Reyes, C. N., Becker, C. A., et al. (2011). Activation of the innate immune receptor Dectin-1 upon formation of a phagocytic synapse. Nature, 472, 471–475. doi.org/10.1038/nature10071
  2. 2Balogh, L., Polyak, A., Mathe, D., et al. (2008). Absorption, uptake and tissue affinity of high-molecular-weight hyaluronan after oral administration in rats and dogs. Journal of Agricultural and Food Chemistry, 56(22), 10582–10593. doi.org/10.1021/jf8017029
  3. 3Graham-Thiers, P. M., & Kronfeld, D. S. (2005). Amino acid supplementation improves muscle mass in aged and young horses. Journal of Animal Science, 83(12), 2783–2788. academic.oup.com
  4. 4Van den Hoven, R., Bauer, A., Hackl, S., et al. (2011). Changes in potential markers of muscle-cell degradation in exercised horses supplemented with a protein and amino acid mixture. Journal of Animal Physiology and Animal Nutrition. doi.org/10.1111/j.1439-0396.2010.01097.x
  5. 5Tanner, S. L., Wagner, A. L., Digianantonio, R. N., et al. (2014). Dietary crude protein intake influences rates of whole-body protein synthesis in weanling horses. The Veterinary Journal. sciencedirect.com
  6. 6Latham, C. M., Wagner, A. L., et al. (2019). Effects of dietary amino acid supplementation on measures of whole-body and muscle protein metabolism in aged horses. Journal of Animal Physiology and Animal Nutrition. doi.org/10.1111/jpn.12992
  7. 7Mastellar, S. L., Coleman, R. J., & Urschel, K. L. (2016). Controlled trial of whole body protein synthesis and plasma amino acid concentrations in yearling horses fed graded amounts of lysine. The Veterinary Journal. sciencedirect.com
  8. 8Mastellar, S. L., Moffet, A., Harris, P. A., & Urschel, K. L. (2016). Effects of threonine supplementation on whole-body protein synthesis and plasma metabolites in growing and mature horses. The Veterinary Journal. sciencedirect.com
  9. 9Pritchard, A. (2020). The role alterations in dietary calcium and silicon balance play on bone and cartilage in horses and poultry. Graduate thesis. proquest.com
  10. 10Nielsen, B. D. (2023). A review of three decades of research dedicated to making equine bones stronger: implications for horses and humans. Animals, 13(5), 789. doi.org/10.3390/ani13050789
  11. 11Logan, A. A., & Nielsen, B. D. (2021). Training young horses: the science behind the benefits. Animals, 11(2), 463. doi.org/10.3390/ani11020463
  12. 12Fowler, A. L., Pyles, M. B., Hayes, S. H., et al. (2022). Effect of weight change on markers of bone turnover and phosphorus excretion. Journal of Equine Veterinary Science. sciencedirect.com
  13. 13Saastamoinen, M., & Valtonen, S. S. E. (2020). The effect of diet composition on the digestibility and fecal excretion of phosphorus in horses: a potential risk of phosphorus leaching? Animals. go.gale.com
  14. 14Carmona, J. U., Argüelles, D., Deulofeu, R., et al. (2009). Effect of the administration of an oral hyaluronan formulation on clinical and biochemical parameters in young horses with osteochondrosis. Veterinary and Comparative Orthopaedics and Traumatology. doi.org/10.3415/VCOT-09-01-0001
  15. 15Niemelä, T. M., Tulamo, R. M., Aaltonen, K., et al. (2018). Changes in biomarkers in equine synovial fluid two weeks after intra-articular hyaluronan treatment: a randomised double-blind clinical trial. BMC Veterinary Research. doi.org/10.1186/s12917-018-1512-2
  16. 16Niemelä, T. M., Tulamo, R. M., Carmona, J. U., et al. (2019). Evaluation of the effect of experimentally induced cartilage defect and intra-articular hyaluronan on synovial fluid biomarkers in intercarpal joints of horses. Acta Veterinaria Scandinavica. doi.org/10.1186/s13028-019-0460-6
  17. 17da Silva Xavier, A. A., da Rosa, P. P., et al. (2021). An assessment of the effectiveness of hyaluronic acid and polyacrylamide hydrogel in horses with osteoarthritis: systematic review and network meta-analysis. Research in Veterinary Science. sciencedirect.com
  18. 18National Research Council. (2007). Nutrient Requirements of Horses, 6th revised edition. National Academies Press. doi.org/10.17226/11653
  19. 19Mandatori, D., Pelusi, L., Schiavone, V., et al. (2021). The dual role of vitamin K2 in bone-vascular crosstalk: opposite effects on bone loss and vascular calcification. Nutrients, 13(4), 1222. doi.org/10.3390/nu13041222
  20. 20Atkins, G. J., Welldon, K. J., Wijenayaka, A. R., et al. (2009). Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by gamma-carboxylation-dependent and independent mechanisms. American Journal of Physiology-Cell Physiology. doi.org/10.1152/ajpcell.00216.2009
  21. 21Yilmaz, I. C., Güler, T., Ekmen, E. G., & Özçelik, M. (2026). The effects of boron mineral on performance, bone and mineral metabolism in Purebred Arabian foals. Biological Trace Element Research. doi.org/10.1007/s12011-026-05138-x
  22. 22Vervuert, I., & Stratton-Phelps, M. (2021). The safety and efficacy in horses of certain nutraceuticals that claim to have health benefits. Veterinary Clinics of North America: Equine Practice. vetequine.theclinics.com
  23. 23Geyer, H., & Schulze, J. (1994). The long-term influence of biotin supplementation on hoof horn quality in horses. Schweizer Archiv für Tierheilkunde, 136, 137–149.
  24. 24Josseck, H., Zenker, W., & Geyer, H. (1995). Hoof horn abnormalities in Lipizzaner horses and the effect of dietary biotin on macroscopic aspects of hoof horn quality. Equine Veterinary Journal, 27(3), 175–182. doi.org/10.1111/j.2042-3306.1995.tb03060.x
  25. 25Zenker, W., Josseck, H., & Geyer, H. (1995). Histological and physical assessment of poor hoof horn quality in Lipizzaner horses and a therapeutic trial with biotin and a placebo. Equine Veterinary Journal, 27(3), 183–191. doi.org/10.1111/j.2042-3306.1995.tb03061.x
  26. 26Burns, T. A. (2021). Feeding the foot: nutritional influences on equine hoof health. Veterinary Clinics of North America: Equine Practice. vetequine.theclinics.com
  27. 27Dittmer, K. E., & Thompson, K. G. (2011). Vitamin D metabolism and rickets in domestic animals: a review. Veterinary Pathology, 48(2), 389–407. doi.org/10.1177/0300985810375240
  28. 28Robles, M., Hammer, C., Staniar, W. B., et al. (2021). Nutrition of broodmares. Veterinary Clinics of North America: Equine Practice. vetequine.theclinics.com
  29. 29Robles, M., Gautier, C., Mendoza, L., et al. (2017). Maternal nutrition during pregnancy affects testicular and bone development, glucose metabolism and response to overnutrition in weaned horses up to two years. PLoS ONE, 12(1), e0169295. doi.org/10.1371/journal.pone.0169295
The $20,000 promise · subscription benefit

Subscribe, and colic surgery stops being a $20,000 decision.

Colic surgery can run $5,000–$20,000+. Because this combo contains Gut X, an enrolled, qualifying subscription backs your horse with up to $20,000 in surgical reimbursement, so the worst day isn’t also a financial one. One-time orders ship without Colic Surgery Coverage.

01

Enroll & subscribe

Complete the enrollment form and keep a qualifying Osteo-MAX + Gut X subscription active. Once accepted, your horse is in the 100X Colic Surgery Coverage Program, subject to eligibility conditions and a 30-day qualifying period. A one-time order does not qualify.

02

Stay covered

Coverage stays active as long as your subscription does. Keep feeding 2 ounces daily for gut support, keep the protection in place.

03

Up to $20,000 reimbursed

If your horse needs colic surgery while enrolled and in compliance, the program reimburses eligible surgical costs up to $20,000 per horse over the horse’s lifetime, with a $0 deductible.

$20,000Max reimbursement / horse$0 deductible
30 daysQualifying period after acceptance
Subscription onlyOne-time orders ship without Colic Surgery Coverage

Colic Surgery Coverage is a reimbursement program, not insurance, and is not a health claim. Eligibility, waiting periods, and terms apply; coverage applies only while a subscription remains active. See full program terms. Switch to Subscribe & Save →

$20,000 Colic Surgery Coverage, on subscription

Because this combo contains Gut X, a qualifying subscription makes your horse eligible for our program: complete the enrollment form, and once accepted, eligible colic-surgery costs are reimbursed up to $20,000 per horse (lifetime) with a $0 deductible after a 30-day qualifying period. One-time orders ship without Colic Surgery Coverage. Colic Surgery Coverage is a reimbursement program, not insurance, and is not a health claim.

100% Satisfaction Guarantee

Every order is backed end to end: free shipping both ways, a real person on the phone at 1-800-677-3574, and a free equine nutritionist consultation if you want help sizing the protocol.

90-Day Money-Back Guarantee

Feed both daily for 90 days. If you don’t see the difference, we refund you, with free shipping on every order.

Subscribe & Save

Put the pair on auto-delivery and lock in a better price on every order. Pause, skip, swap, or change your delivery dates anytime, fully in your control.

Still deciding

Questions, answered.

The 1 + 1 ships one gallon of Osteo-MAX, one gallon of Gut X, and 2 pumpers, one for each jug. The 2 + 2 ships two gallons of each with 4 pumpers, and the 4 + 4 ships four gallons of each with 4 pumpers, two per product. Each gallon is up to a 4 month supply at the maintenance dose. Orders placed before 3:00 pm CST ship the same day, Monday through Friday, with free shipping.
Many owners notice changes from Gut X within 7 to 14 days, most often in body condition, appetite, manure quality, and coat shine. Osteo-MAX works on a longer clock, with most owners reporting changes in movement and comfort within the first 30 days. Neither is a quick fix, and both are backed by our 90-day money-back guarantee.
Yes. They are designed to be fed together on the same feed, and most barns run them as a pair. Both are USEF and FEI compliant with no prohibited substances, so they are cleared for horses showing under either rule set.
Because this combo contains Gut X, a qualifying subscription makes your horse eligible for the $20,000 Colic Surgery Coverage Program: complete the enrollment form, and once accepted, eligible colic-surgery costs are reimbursed up to $20,000 per horse over the horse's lifetime, with a $0 deductible, after a 30-day qualifying period. One-time orders ship without Colic Surgery Coverage. Colic Surgery Coverage is a reimbursement program, not insurance, and is not a health claim.
Your subscription is fully flexible. Manage it anytime in your account or by SMS: pause, change delivery dates, or cancel with no fees and no phone tree.

Start with the foundation.

Osteo-MAX for bone, joint & connective tissue. Gut X for the gut that has to absorb it. Built on Dr. Peterson’s 47+ years of equine medicine.

Get Osteo-MAX + Gut X

Orders before 3:00 pm CST ship the same day, Monday through Friday. Free shipping on every order.
See the guarantee.

A horse and rider in the arena
Gut X, 1 gallon
Osteo-MAX, 1 gallon
One pump of each, every day
196mgBeta Glucan
200mgHyaluronic Acid
6,975mgAmino Acid Blend
430mgSilicon

Beta glucan and hyaluronan from Gut X. Amino acids and silicon from Osteo-MAX. Two pumps, one feeding.

100% Satisfaction Guarantee
90Days

Feed it for 90 days. If your horse is not doing better, we refund you.

90 day returns on every order. Keep feeding it, tell us it did not work, and we send the money back.

Denim outdoors after 90 days on the protocol
The Foundation Stack

Gut X + Osteo-MAX

★★★★★4.9Gut X 16,118Osteo-MAX 8,993

The two areas horses most often need support, in one shipment. Gut X for the gut, Osteo-MAX for joints, soft tissue and bone.

$2.29/day

Save 20% Today

  • Gastric supportCoats and soothes the stomach lining.
  • Body conditionBetter absorption for weight and topline.
  • Colic supportUp to $20,000 in colic surgery coverage.
Beta glucanAmino Acid BlendSilicon
Free shipping 90-day money-back

FREE delivery —. Order within —

Gut X + Osteo-MAX
Product details

Every active is at the upper end of its peer-reviewed efficacy range. No proprietary blends hiding a dose.

Osteo-MAX’s seven actives and its own reference list are on the Osteo-MAX page.

The systemLiquid SystemProprietary liquid carrier99%availability
The proprietary carrier stabilizes, suspends and pre-disperses every active before feeding, supporting uniform dosing and up to 99%1,2,3 availability, while powders and pellets can assimilate as low as 2.5%4.
Beta Glucanβ-1,3 / 1,6 glucan196mg / oz
β-1,3 / 1,6 glucan, a soluble fiber that works on contact with the gut’s immune tissue, supporting a healthy stomach lining and immune response.1,5,6
Hyaluronic AcidSodium hyaluronate200mg / oz
A high molecular weight form of hyaluronic acid that works on contact, helping form a hydrated, protective coating across the stomach and small intestine.2,3,6,7
References
1Goodridge et al. (2011). 10.1038/nature10071
2Balogh et al. (2008). 10.1021/jf8017029
3Sammarco et al. (2019). 10.3390/cells8091074
4Du et al. (2004). 10.1002/bdd.392
5Tsoni & Brown (2008). 10.1196/annals.1443.019
6Andrews et al. (2025). 10.1111/eve.70009
7Misra et al. (2015). 10.3389/fimmu.2015.00201
8Goodridge et al. (2009). 10.1111/j.1600-065X.2009.00793.x
9Picetti et al. (2021). 10.14202/vetworld.2021.835-840
10Lacerenza et al. (2024). 10.3390/ani14030474

Load with 2 pumps a day for the first 30 days, then settle into 1 pump a day.

  • Pump it straight over the existing ration. The liquid coats the feed, so picky eaters take it without a fight.
  • One gallon is 128 maintenance doses, up to a 4 month supply for one horse.
  • The loading phase runs about 30 days.

Most owners notice manure quality, appetite and coat changes in the first week. Gut lining support keeps compounding, with full benefit typically by month 6.

  • Day 1 to 30, the loading dose is doing the work.
  • Day 30 onward, one pump a day holds it.
  • This is daily long-term gut and immune support, not a quick fix.

FREE delivery —. Order within —

The comparison

Why form is the whole game.

The actives are not the differentiator, delivery is. Here is how liquid stacks up against the dry supplements in most feed rooms.

Gut X liquidPowder / pellet
Delivery form
Pre-dispersed liquid, suspendedDry particles, must hydrate
Availability
Up to 99%1,2As low as 2.5%3
Dose accuracy
One pump, exactScoop, settles and separates
Goes to work
On contactMust break down first
Dose consistency
196 mg beta glucan + 200 mg HA, every pumpVaries with settling
References1 Goodridge et al. (2011). 10.1038/nature10071
2 Balogh et al. (2008). 10.1021/jf8017029
3 Du et al. (2004). 10.1002/bdd.392
Why liquid

Ready the moment it hits the gut.

Gut X is delivered in a proprietary liquid form with up to 99% availability1,2. Powders and pellets must first break apart, hydrate and disperse into usable surface area inside a moving gut, a slow, variable process that leaves availability as low as 2.5%3.

1Goodridge et al. (2011)2Balogh et al. (2008)3Du et al. (2004)
Colic Surgery Coverage

Up to $20,000 toward colic surgery.

Included at no extra cost with an enrolled, qualifying subscription. Not insurance you buy, a benefit you keep while you stay on protocol.

01

Enroll & subscribe

Complete the enrollment form and keep a qualifying subscription active. Once accepted, a 30-day qualifying period applies before reimbursement eligibility begins.

02

Stay on protocol

Coverage stays active as long as the subscription does. Pause it and coverage pauses with it.

03

If the worst happens

Submit the surgical invoice and we reimburse up to $20,000 of the cost.

$20,000Maximum lifetime reimbursement per covered horse
$0Additional cost on any subscription

Program terms, eligibility and exclusions apply. One-time orders are not covered. Read the full terms

Who formulates it
Dr. Russ Peterson, DVM
Dr. Russ Peterson, DVM
MS · DACVSMR · Cert. ISELP
Chief Veterinary Officer

Nearly five decades of equine medicine, sport horse performance, rehabilitation and nutrition. Gut X reflects that standard: clinically studied beta glucan and hyaluronic acid, transparent dosing, and a liquid carrier built to keep the actives stable and dispersed.

100% Satisfaction Guarantee

Start the protocol

One pump a day. Feed it for 90 days, and if your horse is not doing better, we refund you.

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